Pietro Lorenzetti
Madonna with Angels Between St. Nicholas and the Prophet Elisha

1328-29
Tempera on wood, 171 x 161 cm
Pinacoteca Nazionale, Siena

This panel with the predella was part of the altarpiece of the Carmelite Church in Siena, which was dismembered in the 16th century. 

More of St. Nicholas

More of the Virgin Enthroned
Source: Web Gallery of Art